excitatory相关论文
Synchronized firing of bursting neurons has been found in many real neural systems.In this paper,a modified bursting Hod......
Contribution of the GABAergic pathway(s) to the correlated activities of chicken retinal ganglion ce
In the present study,the spatiotemporal pattem of chicken retinal ganglion cells firing activity in response to full-fie......
Extremely low-frequency magnetic field is widely used as a noninvasive stimulation method in clinical practice and basic......
The nonlinear mechanism for the same responses of neuronal bursting to opposite self-feedback modula
In the traditional viewpoint,inhibitory and excitatory effects always induce opposite responses.In the present study,the......
Gamma-amino-butyric acid(GABA)-containing interneurons are crucial to both development and function of the brain. Down-r......
Closed-loop control of epileptiform activities in a neural population model using a proportional-der
Epilepsy is believed to be caused by a lack of balance between excitation and inhibitation in the brain. A promising str......
Nociceptin effect on intestinal motility depends on opioidreceptor like-1 receptors and nitric oxide
AIM: To study the effect of the opioid-receptor like-1(ORL1) agonist nociceptin on gastrointestinal(GI)myenteric neurotr......
<正> Lioresal [β-(4-chlorophenyl)-γ-aminobutyric acid] is a GABA-derivative, which not only inhibits the spinal monosy......
SENSITIVITY OF ISOLATED RAT UTERUS TO SYMPATHOMIMETIC AMINES FOLLOWING RESERPINE OR DIETHYLSTILBESTR
<正> Qualitative differences in the actions of various sympathomimetic amines have been proved for many years. Fleckenst......
Autism spectrum disorders(ASD) are highly heterogeneous pediatric developmental disorders with estimated heritability mo......
Association Analysis of Genetic Variant of rs13331 in PSD95 Gene with Autism Spectrum Disorders:A Ca
Autism spectrum disorder(ASD) is a neurodevelopmental disorder characterized by high heritability. Recently, autism, the......
Cellular and Circuitry Bases of Autism: Lessons Learned from the Temporospatial Manipulation of Auti
Transgenic mice carrying mutations that cause Autism Spectrum Disorders(ASDs) continue to be valuable for determining th......
Aim:To evaluate the effects of global system for mobile communications (GSM)1800 MHz microwaves on dendritic filopodia,......
Inhibitory interneurons,which count 10%—20%of neurons in cortex,regulate the firing of excitatory neurons and are criti......
Optical recordings reveal the differential distribution of glutamatergic transmission in the cochlea
Objective Using optical imaging in brainstem slices, we studied evoked responses in the mouse cochlear (CN) and vestibul......
Infant guinea pig retina model of glutamate toxicity and intervention of basic fibroblast growth fac
Impaired vision with oligemic ophthalmopathy is a result of excitotoxicity caused by excitatory amino acids, resulting i......
Effect of nitric oxide synthase inhibitor N~G-nitro-L-arginine on the content of amino acid in ische
BACKGROUND: Nitric oxide synthase (NOS) inhibrtors have been widely used to investigate the role of NO on cerebral ische......
Presynaptic inhibition of nociceptive neurotransmission by somatosensory neuron-secreted suppressors
Noxious stimuli cause pain by activating cutaneous nociceptors.The Aδ-and C-fibers of dorsal root ganglion(DRG) neurons......
It was reported that substance P (SP) is an excitatory neurotransmitter released from nociceptive primary afferent nerv......
Inhibitory effect of morphine on excitatory synaptic transmission via presynaptic mechanism in rat S
Objective: To observe the effects of morphine on the excitatory postsynaptic currents (EPSCs) and miniature EPSCs (mEPSC......
Aim:To examine the basic expression levels of N-methyl-D-aspartate(NMDA)receptor NR 1 and NR2B subunits in six brain re......
Objective: To determine the protective effect of monosialoganglionside (GM1) and evaluate the influence of GM1 on expre......
Objective: To study the effects of chronic lithium on N-methyl-d-aspartate receptor subunit 2B (NR2B) tyrosine phosphory......
Effect of long-term low dose of aspirin on severity of disease following onset of acute cerebral inf
BACKGROUND: Aspirin can decrease the incidence risk of high-risk crowdgroup of cerebral infarction, but there are still ......
BACKGROUND: Aggregation of β-amyloid peptide (Aβ), excitatory intoxication, oxidation injury and inflammation reaction......
BACKGROUND: The high concentration of glutamate release is the main cause for neuronal cell death. The relationship betw......
AIM:To assess the effects of intramuscular analgesics(morphine,Ap-237,pethidine and tramadol)on humanOddi’s sphincter ......
Role of nitric oxide in the impairment of circular muscle contractility of distended, uninflamed mid
AIM: To evaluate the role of nitric oxide (NO) in the motor disorders of the dilated uninflamed mid-colon (DUMC) from tr......
GABAergic neurons are the major inhibitory interneurons that powerfully control the function of spinal neuronal networks......
Effects of various frequency electrical stimulation of the dorsal raphe nucleus on spontaneous firin
BACKGROUND: Some investigations have demonstrated that exogenous 5-hydroxytryptamine increases the spontaneous firing ra......
BACKGROUND: Excitatory amino acids including glutamic acid and aspartic acid play a neurotrophic role during early devel......
Effects of D2 receptor antagonist haloperidol on hippocampal neuronal apoptosis in a rat model of te
BACKGROUND: Dopamine receptors are divided into D1 and D2 subgroups. It has been reported that D2 receptors resist neura......
Inhibitory and excitatory amino acids in the cerebrospinal fluid of children with two types of cereb
BACKGROUND:Under normal conditions,excitatory amino acids are dynamically balanced with inhibi-tory amino acids. Excitat......
Gene expression profiles in the peri-infarct brain cortex in a rat model of stroke-prone renovascula
BACKGROUND:Previous studies have focused on gene expression acutely following stroke onset. However,there have been a fe......
Glutamine synthetase activity and glutamate uptake in hippocampus and frontal cortex in portal hyper
AIM: To study glutamine synthetase (GS) activity and glutamate uptake in the hippocampus and frontal cortex (FC) from ra......
Changes in synaptic and extrasynaptic N-methyl-D-aspartate receptor-mediated currents at early-stage
Previous reports have shown that N-methyl-D-aspartate(NMDA)receptors are extensively involved in epilepsy genesis and re......
Changes of paired-pulse evoked responses during the development of epileptic activity in the hippoca
Dysfunction of inhibitory synaptic transmission can destroy the balance between excitatory and inhibitory synaptic input......
Dynamic expression of cerebral cortex and hippocampal glutamate transporters in a rat model of chest
The present study established a rat model of global cerebral ischemia induced by chest compression for six minutes to dy......
Modulation of cell surface GABA B receptors by desensitization,trafficking and regulated degradation
Inhibitory neurotransmission ensures normal brain function by counteracting and integrating excitatory activity.-Aminobu......
Neutroprotective Efficacy of Sodium Tanshinone B on Hippocampus Neuron in A Rat Model of Focal Cereb
Objective:To investigate the protective effects of sodium tanshinone B(STB) on brain damage following focal ischemia-rep......
Kainic acid can simulate excitatory amino acids in vitro.Neural stem cells,isolated from newborn Wistar rats,were cultur......
Increased function of the TRPV1 channel in small sensory neurons after local inflammation or in vitr
Objective Inflammation at the level of the sensory dorsal root ganglia (DRGs) leads to robust mechanical pain behavior a......
Peripheral and central sensitizations are phenomena that occur during migraine.The role of gabapentin,a migraine prevent......
Achalasia cardia is one of the common causes of motor dysphagia.Though the disease was first described more than 300 yea......
Among the various treatment methods for stroke, increasing attention has been paid to tradi-tional Chinese medicines. Bu......
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In this study postsynaptic potentials responding to the electrical stimulation of the optic nerve and the nucleus isthmi......
OBJECTIVE Temporal lobe epilepsy (TLE) is one of the most common types of human epilepsy, and they are often resistant t......
The structure,function and plasticity of excitatory glutamatergic synapses in the brain are significantly altered by neu......